Koichiro Takahashi Selected Research

CCR3 Receptors

6/2007	A dual antagonist for chemokine CCR3 receptor and histamine H1 receptor.
4/2006	A novel, selective, and orally available antagonist for CC chemokine receptor 3.
1/2006	In vitro and in vivo characterization of a novel CCR3 antagonist, YM-344031.

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Koichiro Takahashi Research Topics

Disease

20	Asthma (Bronchial Asthma) 01/2024 - 01/2006
14	Inflammation (Inflammations) 12/2023 - 01/2006
8	Chronic Obstructive Pulmonary Disease (COPD) 02/2023 - 05/2011
5	Obesity 08/2023 - 06/2017
4	Lung Neoplasms (Lung Cancer) 01/2021 - 01/2016
4	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2019 - 03/2003
3	Dyspnea (Shortness of Breath) 12/2021 - 01/2020
3	Fever (Fevers) 12/2021 - 11/2019
3	Adenocarcinoma 01/2021 - 05/2016
3	Neoplasms (Cancer) 12/2018 - 01/2016
3	Atopic Dermatitis (Atopic Eczema) 01/2017 - 01/2006
2	Respiratory Hypersensitivity 12/2023 - 01/2012
2	Idiopathic Pulmonary Fibrosis 11/2023 - 01/2017
2	Fibrosis (Cirrhosis) 11/2023 - 11/2011
2	Interstitial Lung Diseases (Interstitial Lung Disease) 11/2023 - 04/2017
2	Bronchiectasis 11/2023 - 05/2017
2	Chest Pain (Chest Pains) 12/2021 - 11/2019
2	Pleural Effusion (Pleural Effusions) 01/2021 - 04/2020
2	Immunoglobulin G4-Related Disease 05/2020 - 05/2016
2	Eosinophilia 05/2020 - 01/2012
2	Lung Diseases (Lung Disease) 11/2019 - 05/2016
2	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 05/2019 - 12/2018
2	Nocardia Infections 03/2018 - 05/2017
2	Vomiting 01/2012 - 06/2011
2	Pneumonia (Pneumonitis) 01/2012 - 01/2011
2	Bone Resorption 12/2002 - 08/2002
1	Rheumatoid Arthritis 11/2023
1	B-Cell Lymphoma (Lymphoma, B Cell) 11/2023
1	Weight Loss (Weight Reduction) 08/2023
1	Erythema 01/2021
1	Acute Generalized Exanthematous Pustulosis 01/2021
1	Invasive Pulmonary Aspergillosis 01/2021
1	Cardiovascular Diseases (Cardiovascular Disease) 12/2020
1	Coinfection 08/2020
1	Rheumatic Diseases (Rheumatism) 05/2020
1	Cryptococcosis 04/2020
1	Overweight 01/2020
1	Virus Diseases (Viral Diseases) 01/2020
1	Cough 11/2019

Drug/Important Bio-Agent (IBA)

11	Adrenal Cortex Hormones (Corticosteroids)IBA 12/2023 - 09/2004
8	Biomarkers (Surrogate Marker)IBA 11/2023 - 01/2013
5	CytokinesIBA 12/2023 - 01/2020
5	3- (4- (3- chlorophenyl)- 1- ethyl- 7- methyl- 2- oxo- 1,2- dihydro- 1,8- naphthyridin- 3- yl)propanoic acidIBA 01/2012 - 05/2011
4	RoflumilastIBA 01/2012 - 06/2011
3	Bronchodilator Agents (Bronchodilators)IBA 02/2023 - 01/2020
3	Tyrosine Kinase InhibitorsIBA 01/2021 - 06/2018
3	ErbB Receptors (EGF Receptor)IBA 01/2021 - 06/2018
3	Anti-Bacterial Agents (Antibiotics)IBA 01/2021 - 05/2017
3	MacrolidesIBA 12/2020 - 01/2020
3	Phosphodiesterase 4 InhibitorsIBA 01/2012 - 05/2011
3	CilomilastIBA 01/2012 - 06/2011
3	CCR3 ReceptorsIBA 06/2007 - 01/2006
3	cimadronateIBA 09/2004 - 08/2002
2	Thymic Stromal LymphopoietinIBA 12/2023 - 01/2016
2	PeriostinIBA 11/2023 - 01/2017
2	Fatty Acids (Saturated Fatty Acids)IBA 08/2023 - 06/2017
2	Immunoglobulin E (IgE)IBA 04/2021 - 01/2013
2	Tiotropium Bromide (Spiriva)FDA Link 01/2021 - 01/2020
2	Oxygen (Dioxygen)IBA 01/2021 - 12/2020
2	tiotropium-olodaterolIBA 01/2021 - 01/2020
2	Adrenergic Agonists (Adrenergic Receptor Agonist)IBA 12/2020 - 10/2014
2	Serum AlbuminIBA 12/2020 - 04/2020
2	ChemokinesIBA 01/2020 - 06/2007
2	Sulfamethoxazole Drug Combination Trimethoprim (Co-Trimoxazole)FDA LinkGeneric 03/2018 - 05/2017
2	Proteins (Proteins, Gene)FDA Link 01/2016 - 01/2011
2	LipopolysaccharidesIBA 01/2012 - 11/2007
2	Prednisolone (Predate)FDA LinkGeneric 01/2012 - 11/2011
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2011 - 04/2006
1	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 12/2023
1	Interleukin-5 (Interleukin 5)IBA 12/2023
1	Interleukin-4 (Interleukin 4)IBA 12/2023
1	Interleukin-13IBA 12/2023
1	OzoneIBA 12/2023
1	Leukocyte Common Antigens (CD45 Antigen)IBA 11/2023
1	Azithromycin (Zithromax)FDA LinkGeneric 01/2023
1	fluticasone furoate FDA Link 01/2023
1	vilanterolIBA 01/2023
1	Volatile Fatty AcidsIBA 01/2023
1	GSK573719IBA 01/2023
1	Muscarinic AntagonistsIBA 01/2023
1	AfatinibIBA 01/2021
1	dupilumabIBA 01/2021
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2021
1	Clostridium perfringens epsilon-toxinIBA 01/2021
1	Erlotinib Hydrochloride (CP 358,774)FDA Link 01/2021
1	Fluconazole (Zonal)FDA LinkGeneric 08/2020
1	Immunoglobulin G (IgG)IBA 05/2020
1	C-Reactive ProteinIBA 04/2020
1	Poly I-CIBA 01/2020
1	Chemokine CCL5IBA 01/2020
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2020
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2020

Therapy/Procedure

9	Therapeutics 08/2023 - 09/2004
2	Aftercare (After-Treatment) 04/2020 - 01/2020
2	Drug Therapy (Chemotherapy) 05/2019 - 12/2018
1	Bronchial Thermoplasty 01/2024
1	Traction 11/2023
1	Molecular Targeted Therapy 08/2023
1	Nebulizers and Vaporizers (Inhaler) 01/2023
1	Tooth Extraction (Tooth Extractions) 12/2021